Functional Block Copolymers have the capability to self-assemble into nanoparticles, nanostructured bulk materials, and form highly dense nanoscale architectures on surfaces. We are interested in exploiting nanostructured materials for applications in gene delivery and bioimaging using polyelectrolytes based on cyclopropenium ions. Similarly, the miniaturization of semiconducting nanowires with great sensitivity for contaminants, as well as demonstrating high mobilities will enable the development of next generation light-weight, energy efficient, and portable devices. To this extent, we are synthesizing functional materials and developing viable strategies to control the hierarchical ordering of block copolymers. Using modular materials, we also investigate how nanostructured block copolymers can be interfaced with Van der Waals 2D materials and stem cells.